Guide · Separate IBSA product · Lateral face

Profhilo Structura Singapore: How It Differs from Profhilo

A deeper, more concentrated hyaluronic acid for the sides of the face

Structura shares a maker and a name with Profhilo, but it goes to a different layer for a different reason. It is not a lift or a filler. Results vary.

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In Brief

Profhilo Structura in Singapore places a concentrated hybrid hyaluronic acid into the superficial fat of the lateral face by cannula. It suits early flattening of the sides of the face. It adds no defined volume, does not lift heavy descent and does not remove skin. Results vary.

At a Glance: Profhilo Structura Singapore

What it isA concentrated hybrid hyaluronic acid placed in the superficial fat of the lateral face.
Device or productA separate IBSA product from Profhilo, placed by cannula.
How it worksA cannula enters in front of each ear and places product in superficial fat.
Used forEarly flattening or hollowing of the sides of the face.
What it cannot doStructura adds no defined volume, does not lift heavy descent and does not remove skin.
Main risksSwelling or tenderness around entry points; bruising, infection and vascular risk.

What the Research Shows: Profhilo Structura Singapore

  • A 2024 narrative review, with medical writing supported by the manufacturer and 3 employee authors, summarised laboratory and clinical literature on thermally made hybrid hyaluronic acid complexes, without pooled figures. [3]

Figures describe published study groups, which may have used other devices or protocols. They do not predict your result. Updated 6 November 2026.

About This Topic

What Profhilo Structura is

Profhilo Structura is a separate product from IBSA, the maker of Profhilo. It contains more hybrid high and low molecular weight hyaluronic acid than regular Profhilo. Like Profhilo, it is made by a thermal process with no chemical cross-linking.

The two names are often treated as one product, yet they address different concerns. Being offered one does not mean the other is available. If a quote just says Profhilo, ask which product it refers to.

Profhilo Structura in Singapore: the short answer

Structura is considered when superficial fat has changed and the sides of the face look flatter, yet filler seems more than is needed. Regular Profhilo is the option for thin, crepey or dehydrated skin. For the standard product and the BAP technique, see the Profhilo treatment page and the Profhilo guide.

Profhilo and Structura side by side

ProfhiloProfhilo Structura
Hyaluronic acid in 2 mLLowerHigher
Where it goesInto the skin, at defined BAP pointsSuperficial fat of the lateral face
How it is placedSmall boluses at each pointBy cannula, entering in front of each ear
Aimed atSkin qualityFat-compartment change at the sides of the face
Typical concernCrepey, dull or dehydrated skinEarly flattening of the lateral cheek or area in front of the ear

Why the layer matters

Regular Profhilo goes into the skin at five points on each side. Its target is the quality of the skin. Structura travels by cannula into fat, in the lateral cheek and the area in front of the ear. Its target is that fat compartment. So the two products differ in depth, method and purpose, even though they share a family name. The concentration of hyaluronic acid is higher, but a higher figure does not make it a stronger version of the same treatment. It is simply aimed at a different problem. A face whose sides have flattened is a different problem from dull skin on the surface. That distinction is made at examination, not from a product name.

Who it tends to suit

Lateral hollowing

Early hollowing of the lateral cheek or the area in front of the ear.

Loss of fat support

Early change in fat-compartment support, in a face that does not need conventional filler.

Both concerns

Structura and Profhilo may be combined, with the order decided after examination.

Realistic goals

People who accept that response varies and that the plan is reviewed as it goes.

How treatment is planned

01
Examination
The face is examined to separate skin-quality concerns from fat-compartment change, volume loss and descent.
02
Choice of product
Skin quality points to Profhilo. Lateral flattening points to Structura. Defined volume loss is assessed for filler.
03
Placement
A cannula enters in front of each ear, and product goes into the superficial fat compartments.
04
Series and review
The manufacturer specifies a two-session protocol. Your plan is set at consultation and reviewed against how the tissue responds.

What Profhilo Structura cannot do

Replace filler

It is not a substitute where defined volume is needed. See volume treatment or sunken face treatment.

Lift

It is not a lifting treatment. It does not lift heavy descent. Read the sagging face guide.

Replace bone support

It does not restore what bone loss has taken.

Treat neck or body skin

Crepey neck, décolletage or body skin is assessed for other treatments, such as neck and hand treatment.

Common mix-ups

Same maker, separate product

Sharing a name with Profhilo does not make the two interchangeable.

Deeper does not mean filler

Structura goes deeper than Profhilo but is still not a conventional crosslinked filler.

More hyaluronic acid does not mean a lift

It does not reposition tissue, whatever the concentration.

Not a body treatment

Its placement is described for the lateral face. Neck, décolletage and body skin are assessed for other treatments.

Who should wait or look elsewhere

Tell the doctor about any allergy to hyaluronic acid, active infection or inflammation near the area, pregnancy or breastfeeding, a bleeding disorder or blood thinners, autoimmune disease and earlier filler in the area. These are the cautions that apply to Profhilo, and they are reviewed before any plan is made. Later-stage change is referred to a plastic surgeon. The exam also decides whether Structura is advised at all. Where defined volume is needed, filler is assessed separately, so a consultation may point away from Structura altogether.

Risks and recovery

Swelling or tenderness around the entry points can be expected, and it usually settles. Hyaluronidase can break the product down if needed. As with any injection into the face, discuss bruising, infection and vascular risk with your doctor. Increasing pain, spreading redness or persistent swelling should be reviewed promptly. Results vary between people, and no fixed duration of effect can be stated. Ask how you will be reviewed after each session, because the plan follows the tissue response.

Fees and what to ask

Costs are set out at consultation, after the face has been assessed. Before you agree to anything, ask which product is being offered, how many sessions are planned, where it will be placed and what review is included. These are simple questions, and the answers should be clear. A written plan makes those answers easy to check.

Frequently Asked Questions

It is assessed for early flattening at the sides of the face from fat-compartment change, in a face that does not need filler.
No. They are separate products from IBSA. Structura has more hyaluronic acid and goes into superficial fat by cannula, while Profhilo goes into the skin.
No. It is not a conventional crosslinked filler. It does not replace filler where defined volume is needed.
No. It is not a lifting treatment, and it does not lift heavy descent or remove skin.
The manufacturer specifies a two-session protocol. Your plan is confirmed at consultation and reviewed against your response.
Crepey neck, décolletage or body skin is assessed for other treatments. Structura is described for the lateral face.
Yes. Hyaluronidase can break it down if needed, because it is hyaluronic acid.
SY
Dr Sin Yong
MBBS (NUS) · MRCS (Edinburgh)
MSc Aesthetic Medicine (QMUL) · MSc Practical Dermatology (Cardiff)
Aesthetic physician registered with the Singapore Medical Council.

Find out which product fits your face

Dr Sin Yong will examine you, explain your options and give any fee in writing.

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References

  1. Sparavigna A, Tenconi B Efficacy and tolerance of an injectable medical device containing stable hybrid cooperative complexes of high- and low-molecular-weight hyaluronic acid: a monocentric 16 weeks open-label evaluation. Clin Cosmet Investig Dermatol. 2016;9:297-305. View source · DOI
  2. Koppert E, et al. Hybrid cooperative complex treatment is associated with reduced facial pore size in a pilot study. Sci Rep. 2026;16:26913. View source · DOI
  3. Humzah D, et al. Intradermal Injection of Hybrid Complexes of High- and Low-Molecular-Weight Hyaluronan: Where Do We Stand and Where Are We Headed in Regenerative Medicine?. Int J Mol Sci. 2024;25(6):3216. View source · DOI

Studies may involve other devices or protocols, and they do not predict your own result. See our evidence library and editorial policy.

Related Treatments

Last updated 6 November 2026. General information only. Results vary between individuals.